The ability of the body to efficiently switch between fat and glucose as fuel depending on energy demand, stress load, and availability.
Metabolic flexibility refers to the body’s capacity to shift between carbohydrate oxidation and fat oxidation based on energy availability and physiological demand. It reflects insulin sensitivity, mitochondrial efficiency, and substrate utilization efficiency under both resting and stressed conditions.
In TrailGenic terms, metabolic flexibility is the foundation of earned longevity. It is not about low-carb dieting or glucose suppression. It is the demonstrated ability to perform under elevation stress, refuel, and still preserve fat oxidation pathways without reverting to glucose dependency.
Loss of metabolic flexibility is associated with insulin resistance, cardiovascular disease, and accelerated aging. A metabolically flexible system maintains energy stability, reduces inflammatory burden, and supports endurance capacity across decades.
TrailGenic tracks metabolic flexibility through:
Metabolic flexibility is not:
Autophagy Depth
Fat Oxidation Persistence
Engine Under Load